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CS-W001157 4
Total: USD 88.00

4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline

  • CAS No. 196603-96-0

  • Cat. No. CS-B1293
  • Molecule weight364.17
  • Purity≥98%
  • MDL No.MFCD09955370

*For research and further manufacturing use only, not for direct human use.

4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline|CS-B1293

Structure of 196603-96-0

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General Information

  • CAS No. 196603-96-0
  • Cat. No. CS-B1293
  • Purity ≥98%
  • MDL No. MFCD09955370
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₁BrFN₃O₂
  • Molecular Weight 364.17
  • Synonym(s) 4-[(4-Bromo-2-fluorophenyl)amino]-6-methoxyquinazolin-7-ol
  • SMILES OC1=CC2=NC=NC(NC3=CC=C(Br)C=C3F)=C2C=C1OC

Synthesis

  • Route1
    • 7-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine|CS-B1292
      768350-54-5
    • ~98%
    • In-stock
      4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline|CS-B1293
      196603-96-0

    References

    • THE SCRIPPS RESEARCH INSTITUTE Patent: WO2005/97134 A2, 2005 ; Location in patent: Page/Page column 17-18; figure 2 ; WO 2005/097134 A2
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 42, # 26 p. 5369 - 5389
  • Route3
    • 2-Amino-4-(benzyloxy)-5-methoxybenzamide|CS-0488230
      60547-98-0
    • ~%
    • In-stock
      4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline|CS-B1293
      196603-96-0

    References

    • Journal of Medicinal Chemistry, , vol. 42, # 26 p. 5369 - 5389

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   67.27
  • LogP   3.9892
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   3

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