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CS-W001157 4
Total: USD 88.00

2-(4-Bromophenyl)benzo[d]thiazole

  • CAS No. 19654-19-4

  • Cat. No. CS-0065322
  • Purity≥98%
  • MDL No.MFCD00579199

*For research and further manufacturing use only, not for direct human use.

2-(4-Bromophenyl)benzo[d]thiazole|CS-0065322

Structure of 19654-19-4

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General Information

  • CAS No. 19654-19-4
  • Cat. No. CS-0065322
  • Purity ≥98%
  • MDL No. MFCD00579199
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₈BrNS
  • Molecular Weight 290.18
  • Synonym(s) 2-(4-Bromophenyl)benzothiazole
  • SMILES BrC1=CC=C(C2=NC3=CC=CC=C3S2)C=C1

Description

2-(4-Bromophenyl)benzo[d]thiazole integrates a brominated aryl group with a rigid heterocyclic core, enabling efficient coupling in cross-coupling reactions. This bench-stable scaffold offers enhanced solubility and compatibility in transition-metal-catalyzed transformations, serving as a key building block for functionalized biaryls and advanced materials.

Application

2-(4-Bromophenyl)benzo[d]thiazole serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromo substituent. The benzo[d]thiazole core offers enhanced metabolic stability and favorable electronic properties, making it suitable for constructing complex heterocyclic scaffolds. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient synthesis of advanced intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335-H413
Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   4.7258
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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