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CS-W001157 4
Total: USD 88.00

(2-Bromophenyl)(methyl)sulfane

  • CAS No. 19614-16-5

  • Cat. No. CS-0150107
  • Purity≥98%
  • MDL No.MFCD00000066

*For research and further manufacturing use only, not for direct human use.

(2-Bromophenyl)(methyl)sulfane|CS-0150107

Structure of 19614-16-5

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General Information

  • CAS No. 19614-16-5
  • Cat. No. CS-0150107
  • Purity ≥98%
  • MDL No. MFCD00000066
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BrS
  • Molecular Weight 203.10
  • Synonym(s) Benzene, 1-bromo-2-(methylthio)-
  • SMILES CSC1=CC=CC=C1Br

Description

2-Bromothioanisole has been used in the preparation of:thioether-methyleneborane (PhSCH2B (C6F5)2)21-dimesitylboryl-2-methylthio-benzene

Application

(2-Bromophenyl)(methyl)sulfane serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Negishi couplings. Its bromine substituent provides high reactivity under standard conditions, while the sulfane group offers moderate stability and compatibility with common functional groups. The molecule facilitates efficient construction of biaryl architectures and is particularly useful in the synthesis of heterocyclic scaffolds and pharmaceutical intermediates requiring ortho-substituted aryl motifs.

Synthesis

  • Route1
    • In-stock
      2-Bromobenzenethiol|CS-0022377
      6320-02-1
    • null|null
      74-88-4
    • ~98%
    • In-stock
      (2-Bromophenyl)(methyl)sulfane|CS-0150107
      19614-16-5

    References

    • Liu, Jibing; Chen, Guihua; Xing, Junwei; Liao, Jian Tetrahedron Asymmetry, 2011 , vol. 22, # 5 p. 575 - 579
  • Route2

    References

    • Russian Chemical Bulletin, , vol. 44, # 1 p. 183 - 184 Izvestiya Akademi Nauk, Seriya Khimicheskaya, , # 1 p. 188 - 189
  • Route3
    • null|null
      4856-13-7
    • null|null
      583-53-9
    • ~%
    • In-stock
      (2-Bromophenyl)(methyl)sulfane|CS-0150107
      19614-16-5

    References

    • Journal of the American Chemical Society, , vol. 90, p. 4051 - 4055

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.171
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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