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(5-Methoxypyrimidin-2-yl)methanamine hydrochloride

  • CAS No. 1956318-42-5

  • Cat. No. CS-0053143
  • Molecule weight175.62
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(5-Methoxypyrimidin-2-yl)methanamine hydrochloride|CS-0053143

Structure of 1956318-42-5

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General Information

  • CAS No. 1956318-42-5
  • Cat. No. CS-0053143
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀ClN₃O
  • Molecular Weight 175.62
  • Synonym(s) (5-METHOXYPYRIMIDIN-2-YL)METHANAMINE HCL
  • SMILES Cl.COC1=CN=C(CN)N=C1

Description

This bench-stable, moisture-tolerant amine features a 5-methoxypyrimidin-2-yl scaffold that enables efficient coupling in synthetic sequences. The hydrochloride salt enhances solubility and handling, streamlining integration into pharmaceutical intermediates and functional materials.

Application

(5-Methoxypyrimidin-2-yl)methanamine hydrochloride serves as a versatile building block for pyrimidine-based scaffolds, enabling efficient access to functionalized heterocycles via standard amine coupling and electrophilic substitution reactions. Its bench-stable hydrochloride salt form facilitates handling and purification, while the methoxy group provides orthogonal reactivity in multi-step syntheses. Functions effectively in medicinal chemistry campaigns targeting kinase inhibitors and antiviral agents.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   61.03
  • LogP   0.3657
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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