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CS-W001157 4
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5-Bromooxazole hydrochloride

  • CAS No. 1955557-64-8

  • Cat. No. CS-0469695
  • Molecule weight184.42
  • Purity≥97%
  • MDL No.MFCD29924285

*For research and further manufacturing use only, not for direct human use.

5-Bromooxazole hydrochloride|CS-0469695

Structure of 1955557-64-8

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General Information

  • CAS No. 1955557-64-8
  • Cat. No. CS-0469695
  • Purity ≥97%
  • MDL No. MFCD29924285
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₃BrClNO
  • Molecular Weight 184.42
  • Synonym(s) 5-Bromo-1,3-oxazole hydrochloride
  • SMILES BrC1=CN=CO1.[H]Cl

Description

5-Bromooxazole hydrochloride is a bench-stable heterocyclic building block featuring a bromine substituent at the 5-position of the oxazole ring. This electron-deficient moiety enables direct functionalization in palladium-catalyzed cross-coupling reactions, facilitating rapid access to complex oxazole derivatives. The hydrochloride salt enhances solubility and handling in aqueous and polar organic media.

Application

5-Bromooxazole hydrochloride serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the C5 position of the oxazole ring. Its stability under standard reaction conditions and compatibility with palladium-catalyzed cross-coupling reactions facilitate efficient access to substituted oxazoles. The hydrochloride salt enhances solubility and handling, supporting reliable use in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.03
  • LogP   1.8589
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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