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CS-W001157 4
Total: USD 88.00

Methyl methyl-L-phenylalaninate hydrochloride

  • CAS No. 19460-86-7

  • Cat. No. CS-0147958
  • Purity≥97%
  • MDL No.MFCD00083661

*For research and further manufacturing use only, not for direct human use.

Methyl methyl-L-phenylalaninate hydrochloride|CS-0147958

Structure of 19460-86-7

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General Information

  • CAS No. 19460-86-7
  • Cat. No. CS-0147958
  • Purity ≥97%
  • MDL No. MFCD00083661
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆ClNO₂
  • Molecular Weight 229.70
  • Synonym(s) N-Me-Phe-OMe HCl
  • SMILES O=C(OC)[C@H](CC1=CC=CC=C1)NC.[H]Cl

Description

Methyl methyl-L-phenylalaninate hydrochloride features a protected L-phenylalanine scaffold with enhanced solubility and stability under standard conditions. The zwitterionic character of the hydrochloride salt facilitates handling and integration into peptide synthesis workflows, while the methyl ester group enables selective derivatization. This compound serves as a key building block for bioactive peptide analogs.

Application

Methyl methyl-L-phenylalaninate hydrochloride serves as a stable, bench-ready building block for peptide and peptidomimetic synthesis. Its protected α-amino group and ester functionality enable straightforward coupling reactions with minimal racemization. The hydrochloride salt enhances solubility and handling, facilitating purification and integration into standard solid-phase or solution-phase protocols.

Synthesis

  • Route1
    • null|null
      37553-64-3
    • ~90%
    • In-stock
      Methyl methyl-L-phenylalaninate hydrochloride|CS-0147958
      19460-86-7

    References

    • Ryakhovsky, Vladimir V.; Ivanov, Andrey S. Tetrahedron, 2012 , vol. 68, # 35 p. 7070 - 7076
  • Route2
    • null|null
      67-56-1
    • In-stock
      (S)-2-(Methylamino)-3-phenylpropanoic acid|CS-W005388
      2566-30-5
    • ~90%
    • In-stock
      Methyl methyl-L-phenylalaninate hydrochloride|CS-0147958
      19460-86-7

    References

    • MacDonald, Scott A.; Willson, C. Grant; Chorev, Michael; Vernacchia, Fred S.; Goodman, Murray Journal of Medicinal Chemistry, 1980 , vol. 23, # 4 p. 413 - 420
  • Route3
    • BOC-L-Phenylalanine Bortezomib Impurity|CS-0169695
      13734-34-4
    • ~%
    • In-stock
      Methyl methyl-L-phenylalaninate hydrochloride|CS-0147958
      19460-86-7

    References

    • Ryakhovsky, Vladimir V.; Ivanov, Andrey S. Tetrahedron, 2012 , vol. 68, # 35 p. 7070 - 7076

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317-H334-H350-H372
Precautionary Statements : P260-P261-P264-P270-P272-P280-P284-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.4119
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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