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CS-W001157 4
Total: USD 88.00

(Tetrahydro-2H-pyran-4-yl)hydrazine hydrochloride

  • CAS No. 194543-22-1

  • Cat. No. CS-0047579
  • Purity≥97%
  • MDL No.MFCD09744677
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(Tetrahydro-2H-pyran-4-yl)hydrazine hydrochloride|CS-0047579

Structure of 194543-22-1

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Description

Tetrahydro-2H-pyran-4-yl)hydrazine hydrochloride delivers a stable, moisture-tolerant hydrazine handle for conjugation and functionalization. The tetrahydropyran ring imparts solubility and metabolic stability, while the hydrazinium moiety enables selective coupling reactions under mild conditions. This reagent streamlines access to hydrazone-linked architectures in synthetic and medicinal chemistry workflows.

Application

(Tetrahydro-2H-pyran-4-yl)hydrazine hydrochloride serves as a stable, bench-ready hydrazine equivalent for the construction of pyran-based heterocycles and hydrazide derivatives. Its tetrahydropyranyl protecting group enables orthogonal handling in complex syntheses, while the hydrazine moiety facilitates reliable condensation reactions with carbonyl compounds, enabling access to diverse hydrazone scaffolds under mild conditions.

General Information

  • CAS No. 194543-22-1
  • Cat. No. CS-0047579
  • Purity ≥97%
  • MDL No. MFCD09744677
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃ClN₂O
  • Molecular Weight 152.62
  • Synonym(s) 4-Hydrazinyltetrahydropyran Hydrochloride
  • SMILES NNC1CCOCC1.[H]Cl

Computational Chemistry Data

  • TPSA   47.28
  • LogP   0.0505
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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