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CS-W001157 4
Total: USD 88.00

3-Chloro-2-naphthoic acid

  • CAS No. 19411-56-4

  • Cat. No. CS-0567084
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Chloro-2-naphthoic acid|CS-0567084

Structure of 19411-56-4

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Description

3-Chloro-2-naphthoic acid features a chlorinated naphthalene core with a carboxylic acid group at the 2-position, offering enhanced electron-withdrawal and reactivity. This structural motif enables direct incorporation into pharmaceutical intermediates and functionalized polymers under standard conditions. The compound exhibits robust stability and facilitates efficient coupling reactions in synthetic workflows.

Application

3-Chloro-2-naphthoic acid serves as a versatile building block in the synthesis of pharmaceutical intermediates and functionalized heterocycles. Its naphthoic acid core provides a rigid, planar scaffold with enhanced electrophilicity at the C3 position due to the ortho-chloro substituent. The carboxylic acid group enables direct derivatization via esterification, amide formation, or decarboxylative coupling. Bench-stable and readily purified by recrystallization, it facilitates efficient access to bioactive scaffolds through established transition-metal-catalyzed transformations.

General Information

  • CAS No. 19411-56-4
  • Cat. No. CS-0567084
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₇ClO₂
  • Molecular Weight 206.63
  • Synonym(s) 3-Chloronaphthalene-2-carboxylic acid
  • SMILES O=C(C1=C(Cl)C=C2C=CC=CC2=C1)O

Computational Chemistry Data

  • TPSA   37.3
  • LogP   3.1914
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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