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Structure of 19411-56-4
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3-Chloro-2-naphthoic acid features a chlorinated naphthalene core with a carboxylic acid group at the 2-position, offering enhanced electron-withdrawal and reactivity. This structural motif enables direct incorporation into pharmaceutical intermediates and functionalized polymers under standard conditions. The compound exhibits robust stability and facilitates efficient coupling reactions in synthetic workflows.
3-Chloro-2-naphthoic acid serves as a versatile building block in the synthesis of pharmaceutical intermediates and functionalized heterocycles. Its naphthoic acid core provides a rigid, planar scaffold with enhanced electrophilicity at the C3 position due to the ortho-chloro substituent. The carboxylic acid group enables direct derivatization via esterification, amide formation, or decarboxylative coupling. Bench-stable and readily purified by recrystallization, it facilitates efficient access to bioactive scaffolds through established transition-metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: