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CS-W001157 4
Total: USD 88.00

Benzyl (tert-butoxycarbonyl)-L-tyrosinate

  • CAS No. 19391-35-6

  • Cat. No. CS-0169323
  • Purity≥96%
  • MDL No.MFCD00190840

*For research and further manufacturing use only, not for direct human use.

Benzyl (tert-butoxycarbonyl)-L-tyrosinate|CS-0169323

Structure of 19391-35-6

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General Information

  • CAS No. 19391-35-6
  • Cat. No. CS-0169323
  • Purity ≥96%
  • MDL No. MFCD00190840
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₅NO₅
  • Molecular Weight 371.43
  • Synonym(s) None
  • SMILES OC1=CC=C(C=C1)C[C@@H](C(OCC2=CC=CC=C2)=O)NC(OC(C)(C)C)=O

Description

Benzyl (tert-butoxycarbonyl)-L-tyrosinate features a protected tyrosine side chain with orthogonal functionality, enabling selective deprotection during peptide synthesis. The tert-butoxycarbonyl group provides robust protection under acidic conditions, while the benzyl ester facilitates mild cleavage. This dual protection strategy supports efficient coupling and purification workflows in complex sequence assembly.

Synthesis

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      (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid|CS-W014008
      3978-80-1
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      Benzyl (tert-butoxycarbonyl)-L-tyrosinate|CS-0169323
      19391-35-6

    References

    • Palomo, Claudio; Palomo, Antonio L; Palomo, Francisco; Mielgo, Antonia Organic letters, 2002 , vol. 4, # 23 p. 4005 - 4008
  • Route2
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      (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid benzyl ester|CS-0156262
      42406-77-9
    • null|null
      41840-28-2
    • ~89%
    • In-stock
      Benzyl (tert-butoxycarbonyl)-L-tyrosinate|CS-0169323
      19391-35-6

    References

    • Hirai, Yoshiro; Yakota, Katsuyuki; Yamazaki, Takao; Momose, Takefumi Heterocycles, 1990 , vol. 30, # 2 p. 1101 - 1119
  • Route3

    References

    • Palomo, Claudio; Palomo, Antonio L; Palomo, Francisco; Mielgo, Antonia Organic letters, 2002 , vol. 4, # 23 p. 4005 - 4008

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   3.5714
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   6

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