(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)decanoic acid

Name: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)decanoic acid
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CAS No. 193885-59-5
Cat. No. CS-0101011
Molecule weight409.52
Purity≥97%
MDL No.MFCD01311753

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)decanoic acid|CS-0101011

Structure of 193885-59-5

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General Information

CAS No. 193885-59-5
Cat. No. CS-0101011
Purity ≥97%
MDL No. MFCD01311753
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₅H₃₁NO₄
Molecular Weight 409.52
Synonym(s) None
SMILES O=C(O)[C@H](CCCCCCCC)NC(OCC1C2=CC=CC=C2C3=CC=CC=C13)=O

Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)decanoic acid is a chiral, bench-stable amino acid derivative featuring a bulky fluorenylmethoxycarbonyl (Fmoc) protecting group. This robust N-terminal block facilitates efficient peptide synthesis, enabling high-yield coupling and clean deprotection under mild conditions. The extended aliphatic side chain enhances solubility in organic solvents, streamlining purification workflows.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)decanoic acid serves as a robust, bench-stable amino acid derivative for solid-phase peptide synthesis. The Fmoc group enables efficient deprotection under mild basic conditions, while the aliphatic side chain provides compatibility with diverse coupling protocols. Its well-established reactivity and ease of purification make it a practical choice for constructing complex peptide scaffolds and functionalized building blocks in medicinal chemistry workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 75.63
LogP 5.7289
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 11

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)decanoic acid

CAS No. 193885-59-5

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