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tert-Butyl 3-bromo-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate

  • CAS No. 1936429-06-9

  • Cat. No. CS-0039625
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3-bromo-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate|CS-0039625

Structure of 1936429-06-9

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General Information

  • CAS No. 1936429-06-9
  • Cat. No. CS-0039625
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆BrN₃O₂
  • Molecular Weight 302.17
  • Synonym(s) tert-butyl 3-bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
  • SMILES O=C(N1CCC(NN=C2Br)=C2C1)OC(C)(C)C

Description

tert-Butyl 3-bromo-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate is a bench-stable, moisture-tolerant heterocyclic building block featuring a brominated pyrazolopyridine core. This scaffold integrates readily into late-stage functionalization workflows, enabling efficient access to complex nitrogen-containing architectures via cross-coupling and cyclization strategies.

Application

tert-Butyl 3-bromo-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate serves as a versatile building block for the synthesis of substituted pyrazolopyridine scaffolds. The bromo group enables palladium-catalyzed cross-coupling reactions, while the tert-butyl ester offers stability and convenient deprotection under mild acidic conditions. This compound functions effectively in late-stage functionalization workflows and demonstrates compatibility with diverse functional groups commonly encountered in medicinal chemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   58.22
  • LogP   2.4654
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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