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Structure of 1936252-00-4
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7-Chloroquinoline-5-carboxylic acid features a chlorine substituent at the 7-position and a carboxylic acid group at the 5-position of the quinoline core, enabling direct conjugation or derivatization in synthetic routes. The electron-withdrawing chlorine enhances reactivity at the adjacent ring position, while the carboxylic acid provides a handle for amide formation, esterification, or metal coordination. This structure supports integration into bioactive scaffolds and functional materials.
7-Chloroquinoline-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds via amide coupling or Suzuki-Miyaura cross-coupling. Its ortho-chloro and carboxylic acid functionalities provide orthogonal reactivity for downstream derivatization. The compound exhibits good bench stability and facilitates purification by recrystallization, supporting scalable synthesis of quinoline-based pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: