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Structure of 19311-91-2
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N,N-Diethyl-2-hydroxybenzamide features a hydroxylated aromatic ring paired with two ethyl groups on the amide nitrogen, delivering enhanced solubility and metabolic stability. This configuration supports its role as a key scaffold in bioactive molecule design, particularly in pharmaceutical intermediates requiring balanced lipophilicity and hydrogen-bonding capacity under standard bench conditions.
N,N-Diethyl-2-hydroxybenzamide serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through established coupling and cyclization protocols. Its hydroxyl group facilitates direct derivatization and acts as a handle for orthogonal functionalization, while the amide linkage offers metabolic stability and favorable solubility. The diethyl substitution enhances lipophilicity and modulates electronic properties, supporting its use in target-oriented synthesis. This compound functions reliably in standard peptide-like coupling reactions and exhibits bench stability under routine handling conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: