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Structure of 1931-44-8
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7-Amino-1,8-naphthyridin-2(1H)-one features a fused heterocyclic core with dual nitrogen atoms and a strategically positioned amino group, enabling robust hydrogen bonding and enhanced solubility. This scaffold integrates readily into bioactive molecule design, offering high metabolic stability and favorable electronic properties for medicinal chemistry applications.
7-Amino-1,8-naphthyridin-2(1H)-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles through established functionalization routes. Its amine and carbonyl groups provide orthogonal reactivity for coupling reactions and derivatization, while the fused bicyclic core offers structural rigidity and favorable pharmacophore alignment. The compound exhibits good bench stability and is compatible with standard purification methods, facilitating integration into multi-step synthetic sequences for drug discovery programs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: