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CS-W001157 4
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Potassium trifluoro(thiophen-3-yl)borate

  • CAS No. 192863-37-9

  • Cat. No. CS-0155514
  • Purity≥97%
  • MDL No.MFCD03701626

*For research and further manufacturing use only, not for direct human use.

Potassium trifluoro(thiophen-3-yl)borate|CS-0155514

Structure of 192863-37-9

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General Information

  • CAS No. 192863-37-9
  • Cat. No. CS-0155514
  • Purity ≥97%
  • MDL No. MFCD03701626
  • Storage RT, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃BF₃KS
  • Molecular Weight 190.04
  • Synonym(s) Potassium 3-thiophenetrifluoroborate
  • SMILES C1=CSC=C1[B-](F)(F)F.[K+]

Description

Potassium trifluoro(thiophen-3-yl)borate delivers a stable, bench-ready boron source for Suzuki-Miyaura cross-coupling reactions. The thiophen-3-yl moiety enhances solubility and reactivity, while the trifluoroborate group ensures moisture tolerance and compatibility with diverse reaction conditions. This reagent enables efficient C–C bond formation under mild catalytic protocols.

Application

Potassium trifluoro(thiophen-3-yl)borate serves as a stable, bench-ready boron building block for palladium-catalyzed cross-coupling reactions. It enables efficient C–C bond formation with aryl and vinyl halides under mild conditions, offering high functional group tolerance and predictable regioselectivity. Its thiophene moiety provides a valuable heterocyclic scaffold in medicinal chemistry and materials science applications. The reagent exhibits excellent stability in air and moisture, facilitating straightforward handling and purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   -1.1935
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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