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Structure of 191805-29-5
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tert-Butyl 1-oxo-8-azaspiro[4.5]decane-8-carboxylate is a sterically shielded spirocyclic ketone bearing a bench-stable tert-butyl ester handle. This scaffold integrates a rigid, electron-deficient lactam core with a protected carboxylic acid functionality, enabling direct use in iterative synthesis and late-stage diversification.
tert-Butyl 1-oxo-8-azaspiro[4.5]decane-8-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry and catalytic synthesis. The ketone functionality enables selective reductions, nucleophilic additions, and imine formation, while the protected amine supports sequential functionalization. Its tert-butyl ester facilitates straightforward deprotection under mild acidic conditions, enabling access to bioactive carboxylic acid derivatives. The rigid spirocyclic core enhances conformational control in target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: