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Structure of 1914-60-9
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This benzofuran-based carboxylic acid features a fused bicyclic core with enhanced stability and solubility in polar organic solvents. The dihydrobenzofuran scaffold provides a rigid, electron-rich platform ideal for coupling reactions and integration into bioactive scaffolds.
2,3-Dihydro-1-benzofuran-2-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions under standard conditions. The dihydrobenzofuran core exhibits good bench stability and functional group tolerance, supporting diverse transformations in synthetic workflows. This compound functions as a key building block for the construction of pharmacologically relevant scaffolds in drug discovery programs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: