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CS-W001157 4
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(2S,4S)-tert-Butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate

  • CAS No. 191280-88-3

  • Cat. No. CS-0092096
  • Purity≥98%
  • MDL No.MFCD11617833

*For research and further manufacturing use only, not for direct human use.

(2S,4S)-tert-Butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate|CS-0092096

Structure of 191280-88-3

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General Information

  • CAS No. 191280-88-3
  • Cat. No. CS-0092096
  • Purity ≥98%
  • MDL No. MFCD11617833
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉NO₄
  • Molecular Weight 217.26
  • Synonym(s) Tert-butyl (2s,4s)-4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate
  • SMILES O=C(N1[C@H](CO)C[C@H](O)C1)OC(C)(C)C

Synthesis

  • Route1

    References

    • Jing, Qing; Li, Huiying; Roman, Linda J.; Martasek, Pavel; Poulos, Thomas L.; Silverman, Richard B. ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 1 p. 56 - 60
  • Route2
    • null|null
      1023754-70-2
    • ~99%
    • In-stock
      (2S,4S)-tert-Butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate|CS-0092096
      191280-88-3

    References

    • Watanabe, Akiko; Kiyota, Naotoshi; Yamasaki, Tetsuo; Tanda, Kazuhiro; Miyagoe, Tatsunori; Sakamoto, Masanori; Otsuka, Masami Journal of Heterocyclic Chemistry, 2011 , vol. 48, # 5 p. 1132 - 1139
  • Route3
    • 1-(tert-Butyl) 2-methyl (2s,4s)-4-(benzoyloxy)pyrrolidine-1,2-dicarboxylate|CS-0689935
      121147-94-2
    • ~58%
    • In-stock
      (2S,4S)-tert-Butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate|CS-0092096
      191280-88-3

    References

    • Rajeev; Sanjayan; Ganesh Journal of Organic Chemistry, 1997 , vol. 62, # 15 p. 5169 - 5173

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   70
  • LogP   0.349
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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