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CS-W001157 4
Total: USD 88.00

Ethyl (2-chlorobenzoyl)acetate

  • CAS No. 19112-35-7

  • Cat. No. CS-W022636
  • Purity≥96%
  • MDL No.MFCD03424811

*For research and further manufacturing use only, not for direct human use.

Ethyl (2-chlorobenzoyl)acetate|CS-W022636

Structure of 19112-35-7

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General Information

  • CAS No. 19112-35-7
  • Cat. No. CS-W022636
  • Purity ≥96%
  • MDL No. MFCD03424811
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁ClO₃
  • Molecular Weight None
  • Synonym(s) Ethyl 3-(2-Chloro-Phenyl)-3-Oxopropanoate
  • SMILES CCOC(=O)CC(=O)C1=C(Cl)C=CC=C1

Application

Ethyl (2-chlorobenzoyl)acetate serves as a versatile synthon in heterocyclic synthesis, enabling efficient construction of substituted benzimidazoles and quinolines via condensation and cyclization protocols. The ortho-chloro substituent enhances electrophilic reactivity while maintaining bench stability, facilitating straightforward purification and compatibility with standard coupling reactions. Its dual carbonyl functionality supports diverse transformations, including enolate-mediated alkylation and Michael additions, making it a reliable building block for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   2.4759
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   4

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