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CS-W001157 4
Total: USD 88.00

2-Benzyloxyphenylboronic acid

  • CAS No. 190661-29-1

  • Cat. No. CS-W002801
  • Molecule weight228.06
  • Purity≥97%
  • MDL No.MFCD01632206

*For research and further manufacturing use only, not for direct human use.

2-Benzyloxyphenylboronic acid|CS-W002801

Structure of 190661-29-1

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General Information

  • CAS No. 190661-29-1
  • Cat. No. CS-W002801
  • Purity ≥97%
  • MDL No. MFCD01632206
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₃BO₃
  • Molecular Weight 228.06
  • Synonym(s) None
  • SMILES OB(O)C1=CC=CC=C1OCC2=CC=CC=C2

Description

2-Benzyloxyphenylboronic acid features a phenylboronic acid moiety linked to a benzyloxy group at the ortho position, delivering enhanced stability and solubility in polar organic solvents. This configuration enables efficient Suzuki-Miyaura cross-coupling reactions under mild conditions, facilitating rapid access to complex biaryl architectures in medicinal chemistry and materials synthesis.

Application

2-Benzyloxyphenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures under mild conditions. The benzyloxy group provides orthogonal protection and enhances solubility, while the boronic acid functionality offers excellent stability and compatibility with diverse reaction partners. Its bench-stable nature and straightforward purification make it ideal for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   0.9454
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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