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CS-W001157 4
Total: USD 88.00

(5-Bromo-2-fluorophenyl)methanamine

  • CAS No. 190656-34-9

  • Cat. No. CS-0035830
  • Molecule weight204.04
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(5-Bromo-2-fluorophenyl)methanamine|CS-0035830

Structure of 190656-34-9

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General Information

  • CAS No. 190656-34-9
  • Cat. No. CS-0035830
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BrFN
  • Molecular Weight 204.04
  • Synonym(s) 5-Bromo-2-fluorobenzylamine.
  • SMILES C1=C(C=C(CN)C(=C1)F)Br

Description

(5-Bromo-2-fluorophenyl)methanamine features a strategically positioned bromo and fluoro substituent on the aromatic ring, delivering enhanced electronic modulation and metabolic stability. This bench-stable amine integrates readily into pharmaceutical scaffolds via coupling reactions, offering precise functionalization in late-stage synthesis.

Application

(5-Bromo-2-fluorophenyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated arylamines through standard coupling reactions. Its orthogonal reactivity profile—combining bromide for Pd-catalyzed cross-couplings and fluoride for directed functionalization—facilitates efficient access to complex heterocycles and API intermediates. The compound exhibits good bench stability and is readily purified by distillation or crystallization, supporting scalable synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.0469
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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