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CS-W001157 4
Total: USD 88.00

6-Bromophthalazine

  • CAS No. 19064-74-5

  • Cat. No. CS-W006073
  • Purity≥98%
  • MDL No.MFCD08706238

*For research and further manufacturing use only, not for direct human use.

6-Bromophthalazine|CS-W006073

Structure of 19064-74-5

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General Information

  • CAS No. 19064-74-5
  • Cat. No. CS-W006073
  • Purity ≥98%
  • MDL No. MFCD08706238
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrN₂
  • Molecular Weight 209.04
  • Synonym(s) 6-BROMO-PHTHALAZINE
  • SMILES BrC1=CC2=C(C=NN=C2)C=C1

Description

6-Bromophthalazine features a bromine substituent at the 6-position of the phthalazine core, enabling direct functionalization in cross-coupling reactions. This electron-deficient heterocycle serves as a key intermediate in medicinal chemistry and materials science, offering enhanced reactivity and stability under standard conditions.

Application

6-Bromophthalazine serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the 6-position via palladium-catalyzed cross-coupling reactions. Its well-defined reactivity supports the construction of biologically relevant heterocyclic scaffolds, including fused polycyclic systems and pharmaceutical intermediates. The bromine substituent offers excellent stability under standard bench conditions, facilitates straightforward purification, and exhibits broad compatibility with diverse functional groups—making it ideal for iterative synthesis campaigns and process-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.3923
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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