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CS-W001157 4
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2-Ethoxy-2-oxoacetic acid, potassium salt

  • CAS No. 1906-57-6

  • Cat. No. CS-0046170
  • Purity≥97%
  • MDL No.MFCD00045861

*For research and further manufacturing use only, not for direct human use.

2-Ethoxy-2-oxoacetic acid, potassium salt|CS-0046170

Structure of 1906-57-6

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General Information

  • CAS No. 1906-57-6
  • Cat. No. CS-0046170
  • Purity ≥97%
  • MDL No. MFCD00045861
  • Storage RT, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅KO₄
  • Molecular Weight 156.18
  • Synonym(s) Oxalic Acid Ethyl Ester Potassium Salt
  • SMILES O=C([O-])C(OCC)=O.[K+]

Description

This potassium salt of 2-ethoxy-2-oxoacetic acid delivers a stable, moisture-tolerant source of the reactive ethoxyketone moiety. It integrates readily into synthetic sequences requiring controlled enolization or nucleophilic addition, particularly in heterocycle formation and C–C bond coupling workflows.

Application

2-Ethoxy-2-oxoacetic acid, potassium salt serves as a reliable synthon for the construction of α-keto esters and heterocyclic scaffolds. Its stability under ambient conditions and compatibility with common functional groups facilitate straightforward incorporation into multi-step syntheses. The salt form enhances solubility in polar solvents, enabling efficient reactions in aqueous or mixed solvent systems. It functions effectively in Knoevenagel condensations and as a building block for bioactive molecule synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311
Precautionary Statements : P264-P270-P280-P302+P352-P330-P363-P403-P501

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Computational Chemistry Data

  • TPSA   66.43
  • LogP   -4.6966
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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