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Structure of 190595-65-4
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Cholesterol absorption inhibitor 1 is a potent, selective agent that disrupts intestinal cholesterol uptake. This compound integrates into membrane microdomains to interfere with NPC1L1-mediated transport, offering a targeted approach to modulate systemic cholesterol levels without affecting bile acid synthesis.
Cholesterol absorption inhibitor 1 serves as a well-characterized tool compound for studying intestinal cholesterol uptake. It functions as a potent, selective inhibitor of the Niemann-Pick C1-Like 1 (NPC1L1) protein, enabling research into lipid homeostasis and related metabolic pathways. Its robust bench stability and consistent activity in cell-based assays facilitate reliable screening and mechanistic studies in preclinical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: