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CS-W001157 4
Total: USD 88.00

10H-Dibenzo[b,e][1,4]oxaborinin-10-ol

  • CAS No. 19014-28-9

  • Cat. No. CS-0161827
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

10H-Dibenzo[b,e][1,4]oxaborinin-10-ol|CS-0161827

Structure of 19014-28-9

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General Information

  • CAS No. 19014-28-9
  • Cat. No. CS-0161827
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₉BO₂
  • Molecular Weight 196.01
  • Synonym(s) None
  • SMILES OB1C2=CC=CC=C2OC3=CC=CC=C13

Description

10H-Dibenzo[b,e][1,4]oxaborinin-10-ol delivers a stable, bench-ready boronate moiety with enhanced solubility in polar solvents. This heterocyclic framework features a fused dibenzo structure that imparts rigidity and resistance to protodeboronation, enabling reliable coupling in Suzuki-Miyaura reactions without requiring stringent anhydrous conditions.

Application

10H-Dibenzo[b,e][1,4]oxaborinin-10-ol serves as a stable, bench-friendly boron building block for transition-metal-catalyzed cross-coupling reactions. Its fused heterocyclic structure confers enhanced thermal and oxidative stability compared to traditional boronic acids, enabling reliable coupling with aryl, vinyl, and heteroaryl halides under standard conditions. The molecule exhibits excellent functional group tolerance and facilitates efficient construction of complex biaryl architectures in medicinal chemistry and materials synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   0.8903
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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