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CS-W001157 4
Total: USD 88.00

AC-45594

  • CAS No. 18979-55-0

  • Cat. No. CS-W010645
  • Purity≥97%
  • MDL No.MFCD00002337

*For research and further manufacturing use only, not for direct human use.

AC-45594|CS-W010645

Structure of 18979-55-0

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General Information

  • CAS No. 18979-55-0
  • Cat. No. CS-W010645
  • Purity ≥97%
  • MDL No. MFCD00002337
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₈O₂
  • Molecular Weight 194.27
  • Synonym(s) 4-(Hexyloxy)phenol
  • SMILES CCCCCCOC1=CC=C(O)C=C1

Description

4-(Hexyloxy)phenol features a phenolic hydroxyl group flanked by a hexyloxy substituent, delivering enhanced solubility in organic media while maintaining thermal stability. This combination enables direct incorporation into polymer matrices or as a functional additive in specialty resins and antioxidants.

Application

4-(Hexyloxy)phenol serves as a versatile phenolic building block for the synthesis of functionalized aromatic compounds and liquid crystalline materials. Its aliphatic ether functionality provides enhanced solubility and lipophilicity, enabling efficient incorporation into complex molecular architectures. The phenolic hydroxyl group facilitates direct coupling reactions, including Ullmann and Suzuki-Miyaura transformations, and supports orthogonal protection strategies in multi-step syntheses. Bench-stable and readily purified by recrystallization or column chromatography, it functions effectively in both academic research and industrial process development.

Synthesis

  • Route1
    • null|null
      111-25-1
    • null|null
      123-31-9
    • ~50%
    • In-stock
      AC-45594|CS-W010645
      18979-55-0

    References

    • Saravanan; Ambili; Kannan Reactive and Functional Polymers, 2010 , vol. 70, # 4 p. 217 - 222
  • Route2

    References

    • European Journal of Organic Chemistry, , # 26 p. 5902 - 5916
  • Route3
    • null|null
      123-31-9
    • In-stock
      1-Hexanol|CS-0076046
      111-27-3
    • ~72%
    • In-stock
      AC-45594|CS-W010645
      18979-55-0

    References

    • Wang; Furukawa; Nihro; Kakegawa; Matsumoto; Satoh Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 3 p. 570 - 575 Title/Abstract Full Text View citing articles Show Details Nihro; Furukawa; Sogawa; Wang; Miyataka; Matsumoto; Miki; Satoh Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 3 p. 576 - 579

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335-H411
Precautionary Statements : P261-P273-P280

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   3.3513
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   6

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