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Structure of 189750-98-9
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This biphenyl derivative features a trans-4-propylcyclohexyl group enhancing lipophilicity and conformational rigidity, paired with ethoxy and difluoro substituents that fine-tune electronic distribution and solubility. The para-ethoxy and ortho-difluoro pattern enables precise tuning of steric and electronic properties for advanced materials or pharmaceutical intermediates.
4-Ethoxy-2,3-difluoro-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl serves as a versatile building block in medicinal chemistry, enabling the construction of complex heterocyclic scaffolds and bioactive molecules. The trans-4-propylcyclohexyl moiety provides conformational rigidity and enhanced lipophilicity, while the difluoro substitution pattern facilitates metabolic stability and modulates electronic properties. The ethoxy group offers a handle for further functionalization. This compound exhibits bench stability and compatibility with standard cross-coupling reactions, making it well-suited for iterative synthesis in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: