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CS-W001157 4
Total: USD 88.00

2-(1H-Benzo[d]imidazol-6-yl)propan-2-ol

  • CAS No. 1895550-78-3

  • Cat. No. CS-0775759
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(1H-Benzo[d]imidazol-6-yl)propan-2-ol|CS-0775759

Structure of 1895550-78-3

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General Information

  • CAS No. 1895550-78-3
  • Cat. No. CS-0775759
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂N₂O
  • Molecular Weight 176.22
  • Synonym(s) None
  • SMILES CC(C)(O)C1=CC=C(N=CN2)C2=C1

Description

This bench-stable boronate ester integrates a 1H-benzo[d]imidazol-6-yl moiety with a tertiary alcohol handle, enabling efficient coupling in Suzuki-Miyaura reactions. The electron-rich heterocycle enhances reactivity while the steric bulk of the isopropyl group improves stability and solubility in polar organic solvents.

Application

2-(1H-Benzo[d]imidazol-6-yl)propan-2-ol serves as a stable, bench-ready building block for the synthesis of bioactive heterocycles. Its tertiary alcohol functionality enables straightforward derivatization and enhances solubility in polar media. The benzoimidazole core provides robust structural integrity and favorable π-stacking interactions, making it valuable in medicinal chemistry campaigns targeting kinase inhibitors and GPCR modulators. Functional group tolerance supports its use in multi-step sequences without protection-deprotection cycles.

Safety Information

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Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   48.91
  • LogP   1.7903
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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