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CS-W001157 4
Total: USD 88.00

Boc-12-Ado-OH

  • CAS No. 18934-81-1

  • Cat. No. CS-0154365
  • Purity≥97%
  • MDL No.MFCD00235887

*For research and further manufacturing use only, not for direct human use.

Boc-12-Ado-OH|CS-0154365

Structure of 18934-81-1

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General Information

  • CAS No. 18934-81-1
  • Cat. No. CS-0154365
  • Purity ≥97%
  • MDL No. MFCD00235887
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₃₃NO₄
  • Molecular Weight 315.45
  • Synonym(s) None
  • SMILES CC(OC(NCCCCCCCCCCCC(O)=O)=O)(C)C

Description

Boc-12-Ado-OH features a protected 12-amino-1-deoxyadenosine scaffold, enabling stable incorporation into nucleoside analogs. This bench-stable derivative facilitates efficient coupling reactions in oligonucleotide synthesis and glycosylation workflows, offering reliable access to modified purine building blocks under standard conditions.

Synthesis

  • Route1
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • 12-Aminododecanoic acid|CS-0158382
      693-57-2
    • ~99%
    • In-stock
      Boc-12-Ado-OH|CS-0154365
      18934-81-1

    References

    • Goodwin, Andrew P.; Mynar, Justin L.; Ma, Yingzhong; Fleming, Graham R.; Frechet, Jean M. J. Journal of the American Chemical Society, 2005 , vol. 127, # 28 p. 9952 - 9953
  • Route2
    • null|null
      1031684-74-8
    • ~97%
    • In-stock
      Boc-12-Ado-OH|CS-0154365
      18934-81-1

    References

    • Machida, Shinnosuke; Usuba, Kakeru; Blaskovich, Michelle A.; Yano, Akiko; Harada, Kazuo; Sebti, Said M.; Kato, Nobuo; Ohkanda, Junko Chemistry - A European Journal, 2008 , vol. 14, # 5 p. 1392 - 1401

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P260-P261-P264-P271-P280-P302+P352-P304+P340-P340-P362-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.4967
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   12

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