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1,3-Diethyl 2-cyclopentylpropanedioate

  • CAS No. 18928-91-1

  • Cat. No. CS-0308052
  • Molecule weight228.28
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,3-Diethyl 2-cyclopentylpropanedioate|CS-0308052

Structure of 18928-91-1

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General Information

  • CAS No. 18928-91-1
  • Cat. No. CS-0308052
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₀O₄
  • Molecular Weight 228.28
  • Synonym(s) diethyl cyclopentylpropanedioate
  • SMILES CCOC(=O)C(C1CCCC1)C(=O)OCC

Description

1,3-Diethyl 2-cyclopentylpropanedioate features a sterically hindered cyclopentyl group flanked by two ester-functionalized carbon chains, enabling efficient incorporation into asymmetric synthesis. This diester scaffold delivers enhanced stability under standard conditions and facilitates selective functionalization in complex molecular architectures.

Application

1,3-Diethyl 2-cyclopentylpropanedioate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of substituted cyclopentane derivatives via Michael additions and aldol-type condensations. Its α,α-disubstituted malonate framework offers enhanced stability and predictable reactivity, facilitating clean deprotonation and nucleophilic functionalization. The cyclopentyl group imparts conformational rigidity beneficial for stereocontrolled synthesis, while the diester functionality supports sequential transformations in multistep sequences. Ideal for bench-scale applications requiring robustness and predictable outcomes.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.919
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   5

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