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Methyl 2-(3-methoxyphenyl)acetate

  • CAS No. 18927-05-4

  • Cat. No. CS-0081810
  • Purity≥97%
  • MDL No.MFCD00017205

*For research and further manufacturing use only, not for direct human use.

Methyl 2-(3-methoxyphenyl)acetate|CS-0081810

Structure of 18927-05-4

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General Information

  • CAS No. 18927-05-4
  • Cat. No. CS-0081810
  • Purity ≥97%
  • MDL No. MFCD00017205
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₃
  • Molecular Weight 180.20
  • Synonym(s) Methyl 3-methoxyphenylacetate
  • SMILES COC1=CC=CC(CC(OC)=O)=C1

Description

Methyl 2-(3-methoxyphenyl)acetate is a bench-stable, moisture-tolerant ester featuring a para-methoxy-substituted phenyl ring that enables efficient coupling reactions. This aromatic methyl ester integrates readily into synthetic sequences requiring electron-rich aryl handles, delivering predictable reactivity under standard conditions.

Application

Methyl 2-(3-methoxyphenyl)acetate serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient access to substituted benzyl motifs. Its ortho-methoxy substitution pattern enhances regioselective functionalization, while the ester group facilitates downstream transformations such as hydrolysis, reduction, or coupling reactions. Bench-stable and readily purified by distillation or flash chromatography, it functions reliably in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   1.4107
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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