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CS-W001157 4
Total: USD 88.00

4-(But-3-yn-1-yl)piperidine hydrochloride

  • CAS No. 1885090-83-4

  • Cat. No. CS-0142920
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(But-3-yn-1-yl)piperidine hydrochloride|CS-0142920

Structure of 1885090-83-4

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General Information

  • CAS No. 1885090-83-4
  • Cat. No. CS-0142920
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆ClN
  • Molecular Weight 173.68
  • Synonym(s) None
  • SMILES C#CCCC1CCNCC1.Cl

Description

4-(But-3-yn-1-yl)piperidine hydrochloride features a terminal alkyne handle attached to a piperidine core, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation. The hydrochloride salt enhances solubility and stability in aqueous media, facilitating use in synthetic and biochemical workflows.

Application

4-(But-3-yn-1-yl)piperidine hydrochloride serves as a versatile building block for alkyne-functionalized nitrogen heterocycles, enabling efficient access to diverse scaffolds via copper-catalyzed azide-alkyne cycloaddition (CuAAC). The terminal alkyne group exhibits high reactivity in click chemistry applications, while the piperidine nitrogen provides a stable, readily derivatizable site. Bench-stable and easily purified, it functions effectively in both small-molecule library synthesis and medicinal chemistry campaigns requiring bioorthogonal handles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.8212
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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