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CS-W001157 4
Total: USD 88.00

4-(1-Bromoethyl)-6-chloro-5-fluoropyrimidine

  • CAS No. 188416-28-6

  • Cat. No. CS-0001499
  • Molecule weight239.47
  • Purity95+%
  • MDL No.MFCD08458246

*For research and further manufacturing use only, not for direct human use.

4-(1-Bromoethyl)-6-chloro-5-fluoropyrimidine|CS-0001499

Structure of 188416-28-6

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General Information

  • CAS No. 188416-28-6
  • Cat. No. CS-0001499
  • Purity 95+%
  • MDL No. MFCD08458246
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrClFN₂
  • Molecular Weight 239.47
  • Synonym(s) Voriconazole Impurity 4
  • SMILES FC1=C(Cl)N=CN=C1C(C)Br

Synthesis

  • Route1

    References

    • VIAMET PHARMACEUTICALS, INC. Patent: WO2008/64311 A2, 2008 ; Location in patent: Page/Page column 148 ;
  • Route2
    • 2,4-Dichloro-6-ethyl-5-fluoropyrimidine|CS-0137587
      137234-85-6
    • ~%
    • 4-(1-Bromoethyl)-6-chloro-5-fluoropyrimidine|CS-0001499
      188416-28-6

    References

    • Organic Process Research and Development, , vol. 5, # 1 p. 28 - 36
  • Route3

    References

    • Organic Process Research and Development, , vol. 5, # 1 p. 28 - 36

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.725
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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