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Structure of 188359-85-5
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This chiral building block features a hydroxymethyl-functionalized butenyl backbone paired with a tert-butyl carbamate protecting group. The (1R) stereochemistry ensures high enantioselectivity in downstream transformations, while the pendant hydroxyl and alkene moieties enable selective derivatization. Bench-stable and moisture-tolerant, it integrates seamlessly into complex molecule synthesis workflows.
(1R)-(1-Hydroxymethyl-but-3-enyl)-carbamic acid tert-butyl ester serves as a versatile chiral building block for synthesizing functionalized pyrrolidines and other nitrogen-containing heterocycles. The terminal alkene enables palladium-catalyzed coupling reactions, while the protected carbamate and allylic hydroxyl group offer orthogonal reactivity. Bench-stable and amenable to standard purification protocols, it facilitates efficient access to complex scaffolds in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: