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CS-W001157 4
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Benzyl N-(2-aminoethyl)carbamate hydrochloride

  • CAS No. 18807-71-1

  • Cat. No. CS-W008518
  • Purity≥98%
  • MDL No.MFCD00270150

*For research and further manufacturing use only, not for direct human use.

Benzyl N-(2-aminoethyl)carbamate hydrochloride|CS-W008518

Structure of 18807-71-1

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General Information

  • CAS No. 18807-71-1
  • Cat. No. CS-W008518
  • Purity ≥98%
  • MDL No. MFCD00270150
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅ClN₂O₂
  • Molecular Weight 230.69
  • Synonym(s) None
  • SMILES Cl.O=C(OCC=1C=CC=CC1)NCCN

Description

Benzyl N-(2-aminoethyl)carbamate hydrochloride delivers a bifunctional scaffold featuring a primary amine and a carbamate-linked benzyl group. This bench-stable derivative enables efficient conjugation strategies in peptide synthesis and chemical biology applications, combining solubility in aqueous and organic media with predictable reactivity under standard conditions.

Application

Benzyl N-(2-aminoethyl)carbamate hydrochloride serves as a versatile bifunctional building block in peptide and medicinal chemistry, enabling efficient synthesis of amino acid derivatives and peptidomimetics. The pendant primary amine and carbamate functionalities offer orthogonal reactivity for selective conjugation and protection strategies. Its crystalline form ensures excellent bench stability and ease of handling, while the hydrochloride salt enhances solubility in aqueous and polar organic media, facilitating downstream transformations in standard synthetic workflows.

Synthesis

  • Route1

    References

    • Wakamiya, Tateaki; Kamata, Makoto; Kusumoto, Shoichi; Kobayashi, Hiroyuki; Sai, Yoshimichi; Tamai, Ikumi; Tsuji, Akira Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 3 p. 699 - 709
  • Route2
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      61495-86-1
    • ~%
    • In-stock
      Benzyl N-(2-aminoethyl)carbamate hydrochloride|CS-W008518
      18807-71-1

    References

    • US6759509 B1, ;
  • Route3
    • Benzyl N-(2-carbamoylethyl)carbamate|CS-0205177
      886-64-6
    • ~75%
    • In-stock
      Benzyl N-(2-aminoethyl)carbamate hydrochloride|CS-W008518
      18807-71-1

    References

    • Eisenbrand; Lauck-Birkel; Tang Synthesis, 1996 , # 10 p. 1246 - 1258

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   1.2933
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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