Lot numbers can be found on the outside label of a product:
(2-Amino-4-methoxyphenyl)methanol
-
CAS No. 187731-65-3
- Cat. No. CS-0150495
- Purity≥98%
- MDL No.MFCD08275454
*For research and further manufacturing use only, not for direct human use.
Structure of 187731-65-3
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 187731-65-3
- Cat. No. CS-0150495
- Purity ≥98%
- MDL No. MFCD08275454
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₁₁NO₂
- Molecular Weight 153.18
- Synonym(s) Benzenemethanol, 2-amino-4-methoxy- (9CI)
- SMILES COC1=CC(=C(C=C1)CO)N
Description
This bench-stable phenolic alcohol features a strategically positioned amino group and methoxy substituent, enabling direct incorporation into bioactive scaffolds. The ortho-aminomethoxy motif facilitates efficient coupling reactions under mild conditions, delivering functionalized intermediates for medicinal chemistry applications.
Application
(2-Amino-4-methoxyphenyl)methanol serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient access to substituted aniline derivatives. Its ortho-amino and methoxy functionalities offer directed metallation and selective functionalization potential. The benzylic alcohol group facilitates downstream transformations such as oxidation, etherification, or coupling reactions. Exhibiting good bench stability and compatibility with standard protecting group strategies, it functions reliably in multi-step synthetic sequences.
Synthesis
-
Route1
-
In-stock
4294-95-5 - ~64%
-
In-stock
187731-65-3
References
-
Ida, Yoshihiro; Matsubara, Ayaka; Nemoto, Toru; Saito, Manabu; Hirayama, Shigeto; Fujii, Hideaki; Nagase, Hiroshi Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 19 p. 5810 - 5831
-
-
Route2
-
22996-23-2 - ~24%
-
In-stock
187731-65-3
References
-
ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/134378 A1, 2006 ; Location in patent: Page/Page column 110 ; WO 2006/134378 A1
-
-
Route3
-
In-stock
33844-21-2 - ~%
-
In-stock
187731-65-3
References
-
Reck, Folkert; Alm, Richard; Brassil, Patrick; Newman, Joseph; Dejonge, Boudewijn; Eyermann, Charles J.; Breault, Gloria; Breen, John; Comita-Prevoir, Janelle; Cronin, Mark; Davis, Hajnalka; Ehmann, David; Galullo, Vincent; Geng, Bolin; Grebe, Tyler; Morningstar, Marshall; Walker, Phil; Hayter, Barry; Fisher, Stewart Journal of Medicinal Chemistry, 2011 , vol. 54, # 22 p. 7834 - 7847
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 55.48
- LogP 0.7697
- H_Acceptors 3
- H_Donors 2
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- (2-Amino-4-methoxyphenyl)methanol sigma(2-Amino-4-methoxyphenyl)methanol manufacturer(2-Amino-4-methoxyphenyl)methanol price(2-Amino-4-methoxyphenyl)methanol structure(2-Amino-4-methoxyphenyl)methanol SDSbuy (2-Amino-4-methoxyphenyl)methanol(2-Amino-4-methoxyphenyl)methanol supplier(2-Amino-4-methoxyphenyl)methanol uses(2-Amino-4-methoxyphenyl)methanol molecular weightprice of (2-Amino-4-methoxyphenyl)methanol(2-Amino-4-methoxyphenyl)methanol chemical name formula of (2-Amino-4-methoxyphenyl)methanol