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CS-W001157 4
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1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl tetrahydro-2H-pyran-4-carboxylate

  • CAS No. 1872262-74-2

  • Cat. No. CS-0652828
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl tetrahydro-2H-pyran-4-carboxylate|CS-0652828

Structure of 1872262-74-2

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General Information

  • CAS No. 1872262-74-2
  • Cat. No. CS-0652828
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₃NO₅
  • Molecular Weight 275.26
  • Synonym(s) None
  • SMILES O=C(C1CCOCC1)ON(C(C2=C3C=CC=C2)=O)C3=O

Description

This tetrahydro-2H-pyran-4-carboxylate integrates a reactive isoindoline scaffold with a stable, moisture-tolerant pyran ring. The dihydroisoindole core enables efficient coupling in synthetic sequences, while the protected carboxylate facilitates selective derivatization under mild conditions.

Application

1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl tetrahydro-2H-pyran-4-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of complex heterocyclic scaffolds. Its fused isoindoline core and protected carboxylic acid functionality offer enhanced bench stability and compatibility with standard coupling reactions. The molecule facilitates orthogonal functional group manipulation and is particularly valuable in the synthesis of bioactive compounds requiring precise stereochemical control and structural rigidity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   72.91
  • LogP   1.1674
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

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