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Structure of 18706-39-3
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2-(Trifluoromethyl)quinoline-4-carboxylic acid integrates a trifluoromethyl group at the 2-position and a carboxylic acid at the 4-position of the quinoline scaffold, delivering enhanced electron-withdrawing character and improved solubility in polar solvents. This configuration enables direct incorporation into bioactive scaffolds and conjugation workflows under standard conditions.
2-(Trifluoromethyl)quinoline-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid facilitates direct derivatization or salt formation. The molecule exhibits bench stability and compatibility with common synthetic protocols, making it well-suited for lead optimization and API intermediate development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: