Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,3-Dimethoxypropan-2-one

  • CAS No. 18664-32-9

  • Cat. No. CS-W007070
  • Purity≥96%
  • MDL No.MFCD00270306

*For research and further manufacturing use only, not for direct human use.

1,3-Dimethoxypropan-2-one|CS-W007070

Structure of 18664-32-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 18664-32-9
  • Cat. No. CS-W007070
  • Purity ≥96%
  • MDL No. MFCD00270306
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀O₃
  • Molecular Weight 118.13
  • Synonym(s) 2-propanone, 1,3-dimethoxy-
  • SMILES O=C(COC)COC

Description

1,3-Dimethoxypropan-2-one is a bench-stable, moisture-tolerant ketone featuring two methoxy groups flanking a carbonyl center. This configuration enhances electrophilicity at the central carbon while improving solubility in polar organic solvents. The molecule serves as a key building block in synthesizing heterocycles and functionalized intermediates for medicinal chemistry and polymer science applications.

Application

1,3-Dimethoxypropan-2-one serves as a versatile synthon in organic synthesis, enabling efficient construction of heterocyclic scaffolds and functionalized carbon chains. Its α,β-unsaturated ketone reactivity facilitates nucleophilic additions and Michael-type processes under mild conditions. The molecule exhibits good bench stability and ease of purification, making it suitable for use in multi-step sequences involving esterification, condensation, or cyclization reactions common in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Cho, Hidetsura; Katoh, Susumu; Sayama, Shinsuke; Murakami, Kengo; Nakanishi, Hiroyuki; Kajimoto, Yasuyuki; Ueno, Hiroshi; Kawasaki, Hisashi; Aisaka, Kazuo; Uchida, Itsuo Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3797 - 3805
  • Route2
    • null|null
      130895-62-4
    • ~%
    • In-stock
      1,3-Dimethoxypropan-2-one|CS-W007070
      18664-32-9

    References

    • Adkins et al. Journal of the American Chemical Society, 1949 , vol. 71, p. 3622,3623 Full Text Show Details Henze; Rogers Journal of the American Chemical Society, 1939 , vol. 61, p. 433
  • Route3
    • null|null
      23230-92-4
    • ~%
    • In-stock
      1,3-Dimethoxypropan-2-one|CS-W007070
      18664-32-9

    References

    • Animati, Fabio; Berettoni, Marco; Bigioni, Mario; Binaschi, Monica; Cipollone, Amalia; Irrissuto, Clelia; Nardelli, Federica; Olivieri, Lauso Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 15 p. 5013 - 5017

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   35.53
  • LogP   -0.1517
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   4

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1,3-Dimethoxypropan-2-one sigma1,3-Dimethoxypropan-2-one manufacturer1,3-Dimethoxypropan-2-one price1,3-Dimethoxypropan-2-one structure1,3-Dimethoxypropan-2-one SDSbuy 1,3-Dimethoxypropan-2-one1,3-Dimethoxypropan-2-one supplier1,3-Dimethoxypropan-2-one uses1,3-Dimethoxypropan-2-one molecular weightprice of 1,3-Dimethoxypropan-2-one1,3-Dimethoxypropan-2-one chemical name formula of 1,3-Dimethoxypropan-2-one
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label