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N6-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-((allyloxy)carbonyl)-L-lysine

  • CAS No. 186350-56-1

  • Cat. No. CS-0142644
  • Purity≥97%
  • MDL No.MFCD09263339

*For research and further manufacturing use only, not for direct human use.

N6-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-((allyloxy)carbonyl)-L-lysine|CS-0142644

Structure of 186350-56-1

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General Information

  • CAS No. 186350-56-1
  • Cat. No. CS-0142644
  • Purity ≥97%
  • MDL No. MFCD09263339
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₈N₂O₆
  • Molecular Weight 452.50
  • Synonym(s) Alloc-Lys(Fmoc)-OH
  • SMILES O=C(O)[C@H](CCCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)NC(OCC=C)=O

Description

N6-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-((allyloxy)carbonyl)-L-lysine is a dual-protected lysine derivative designed for solid-phase peptide synthesis. The fluorenylmethoxycarbonyl group enables efficient Nα protection with orthogonal deprotection, while the allyloxycarbonyl moiety offers stable, mild cleavage under palladium conditions. This combination facilitates precise chain elongation and simplifies purification in complex sequence assembly.

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Computational Chemistry Data

  • TPSA   113.96
  • LogP   4.0608
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   11

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