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CS-W001157 4
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tert-Butyl 4-phenyl-3,6-dihydro-2H-pyridine-1-carboxylate

  • CAS No. 186347-72-8

  • Cat. No. CS-0037476
  • Purity98+%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-phenyl-3,6-dihydro-2H-pyridine-1-carboxylate|CS-0037476

Structure of 186347-72-8

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General Information

  • CAS No. 186347-72-8
  • Cat. No. CS-0037476
  • Purity 98+%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₁NO₂
  • Molecular Weight 259.34
  • Synonym(s) Tert-butyl 4-phenyl-5,6-dihydropyridine-1(2H)-carboxylate
  • SMILES CC(C)(C)OC(=O)N1CC=C(CC1)C2=CC=CC=C2

Synthesis

  • Route1

    References

    • JANSSEN PHARMACEUTICA N.V. Patent: WO2008/79255 A1, 2008 ; Location in patent: Page/Page column 24 ;
  • Route2
    • null|null
      108-86-1
    • null|null
      79099-07-3
    • ~68%
    • tert-Butyl 4-phenyl-3,6-dihydro-2H-pyridine-1-carboxylate|CS-0037476
      186347-72-8

    References

    • Lee, Ju-Hyeon; Seo, Seon Hee; Lim, Eun Jeong; Cho, Nam-Chul; Nam, Ghilsoo; Kang, Soon Bang; Pae, Ae Nim; Jeong, Nakcheol; Keum, Gyochang European Journal of Medicinal Chemistry, 2014 , vol. 74, p. 246 - 257
  • Route3
    • null|null
      856684-31-6
    • null|null
      100-59-4
    • ~90%
    • tert-Butyl 4-phenyl-3,6-dihydro-2H-pyridine-1-carboxylate|CS-0037476
      186347-72-8

    References

    • Larsen, Uffe S.; Martiny, Lars; Begtrup, Mikael Tetrahedron Letters, 2005 , vol. 46, # 24 p. 4261 - 4263

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   3.7108
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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