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CS-W001157 4
Total: USD 88.00

4-(3,5-Dimethyl-1H-pyrazol-4-yl)benzoic acid

  • CAS No. 185252-69-1

  • Cat. No. CS-0110914
  • Purity≥97%
  • MDL No.MFCD03425153
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(3,5-Dimethyl-1H-pyrazol-4-yl)benzoic acid|CS-0110914

Structure of 185252-69-1

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Description

This pyrazole-carboxylic acid integrates a sterically hindered, electron-rich pyrazole core with a para-substituted benzoic acid moiety. The structure enables robust conjugation in bioconjugation workflows and facilitates incorporation into functionalized polymers or small-molecule probes under standard conditions.

Application

4-(3,5-Dimethyl-1H-pyrazol-4-yl)benzoic acid serves as a versatile building block for constructing bioactive heterocyclic scaffolds. Its pyrazole core exhibits robust bench stability and tolerates a range of functional groups, enabling efficient coupling reactions in medicinal chemistry workflows. The carboxylic acid functionality facilitates direct derivatization or amide formation, supporting rapid access to diverse analogs for structure-activity relationship studies.

General Information

  • CAS No. 185252-69-1
  • Cat. No. CS-0110914
  • Purity ≥97%
  • MDL No. MFCD03425153
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₂N₂O₂
  • Molecular Weight 216.24
  • Synonym(s) 4-(3,5-Dimethyl-4-pyrazolyl)benzoic Acid
  • SMILES O=C(O)C1=CC=C(C=C1)C=2C(=NNC2C)C

Computational Chemistry Data

  • TPSA   65.98
  • LogP   2.39174
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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