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Structure of 184848-89-3
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4-Amino-1,1,1-trifluorobut-3-en-2-one features a trifluoromethyl group flanked by an enone system and a primary amine, enabling direct conjugation with electrophilic partners. This structure supports efficient incorporation into bioactive scaffolds and facilitates rapid derivatization under mild conditions. The compound exhibits enhanced solubility in polar organic solvents and stability under standard bench handling protocols.
4-Amino-1,1,1-trifluorobut-3-en-2-one serves as a versatile building block in synthetic organic chemistry, enabling the construction of fluorinated heterocycles and bioactive scaffolds. Its α,β-unsaturated enone functionality facilitates Michael additions and conjugate functionalizations, while the trifluoromethyl group enhances metabolic stability and modulates lipophilicity. The molecule exhibits good bench stability and compatibility with common protecting groups, supporting efficient downstream transformations in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: