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Structure of 18474-60-7
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7-Methyl-1H-indole-2-carboxylic acid features a sterically hindered indole core with a methyl group at the 7-position and a carboxylic acid functional group at C2, enabling direct coupling reactions in synthetic peptide and pharmaceutical applications. This bench-stable derivative combines enhanced solubility with predictable reactivity, streamlining incorporation into complex molecular architectures under standard conditions.
7-Methyl-1H-indole-2-carboxylic acid serves as a versatile building block for indole-based scaffolds in medicinal chemistry and materials science. Its carboxylic acid functionality enables direct coupling reactions, including amide formation and esterification, while the methyl group enhances metabolic stability. The molecule exhibits good bench stability and facilitates purification via recrystallization or column chromatography. It functions effectively in standard peptide coupling protocols and is compatible with a range of functional groups, making it suitable for modular synthesis of bioactive compounds and heterocyclic derivatives.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: