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Structure of 184163-56-2
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4-Hydrazinyl-3-(trifluoromethyl)benzonitrile features a hydrazinyl group conjugated to an electron-deficient aryl ring bearing a trifluoromethyl and nitrile moiety. This arrangement enables efficient coupling in heterocyclic synthesis, particularly for constructing triazoles and pyrazoles under mild conditions. The molecule exhibits enhanced solubility in polar aprotic solvents and stability during storage, facilitating its use in multistep transformations.
4-Hydrazinyl-3-(trifluoromethyl)benzonitrile serves as a versatile building block for heterocyclic synthesis, enabling efficient access to triazoles, pyrazoles, and other nitrogen-rich scaffolds via cycloaddition or condensation reactions. The hydrazinyl group exhibits high reactivity with electrophiles, while the trifluoromethyl and nitrile functionalities provide excellent electronic modulation and synthetic handle compatibility. Bench-stable and readily purified by recrystallization, it functions effectively in both small-molecule discovery and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: