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CS-W001157 4
Total: USD 88.00

2-Chloroadenine

  • CAS No. 1839-18-5

  • Cat. No. CS-W017715
  • Purity≥98%
  • MDL No.MFCD00037925

*For research and further manufacturing use only, not for direct human use.

2-Chloroadenine|CS-W017715

Structure of 1839-18-5

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General Information

  • CAS No. 1839-18-5
  • Cat. No. CS-W017715
  • Purity ≥98%
  • MDL No. MFCD00037925
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄ClN₅
  • Molecular Weight 169.57
  • Synonym(s) 6-Amino-2-chloropurine
  • SMILES NC1=C2NC=NC2=NC(Cl)=N1

Description

Non-essential amino acid for human development. Precursor for the synthesis of thyroid hormones and select neurotransmitters, such as dopamine and norepinephrine.

Application

2-Chloroadenine serves as a key building block in purine chemistry, enabling site-specific functionalization at the 2-position of the adenine scaffold. Its reactivity facilitates nucleophilic substitution reactions under mild conditions, making it valuable for synthesizing substituted adenine derivatives used in medicinal chemistry and nucleoside analog development. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its utility in scalable synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   80.48
  • LogP   0.5885
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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