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Structure of 183288-46-2
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This piperazinyl-substituted benzofuran scaffold integrates a hydrogen-bonding amide functionality with a basic piperazine ring, enabling versatile coordination in medicinal chemistry. The fused heterocyclic core provides rigidity and enhanced solubility, while the para-piperazinyl group offers tunable polarity for target engagement.
5-(Piperazin-1-yl)benzofuran-2-carboxamide serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amide coupling and functional group interconversions. Its benzofuran core provides structural rigidity and π-stacking potential, while the piperazinyl moiety offers hydrogen-bonding capacity and solubility enhancement. The compound exhibits bench stability and facilitates purification via standard chromatographic methods, making it well-suited for iterative synthesis campaigns in drug discovery programs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: