Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-bromo-3,5-dinitro-Benzene

  • CAS No. 18242-39-2

  • Cat. No. CS-M0502
  • Purity≥98%
  • MDL No.MFCD00156596

*For research and further manufacturing use only, not for direct human use.

1-bromo-3,5-dinitro-Benzene|CS-M0502

Structure of 18242-39-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 18242-39-2
  • Cat. No. CS-M0502
  • Purity ≥98%
  • MDL No. MFCD00156596
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrN₂O₄
  • Molecular Weight 247.00
  • Synonym(s) 1-Bromo-3,5-dinitrobenzene
  • SMILES BrC1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1

Description

1-Bromo-3,5-dinitrobenzene features two strongly electron-withdrawing nitro groups flanking a bromine substituent, creating a highly reactive site for nucleophilic aromatic substitution. This configuration enables efficient coupling with diverse amines and thiols under mild conditions, making it ideal for constructing complex heterocycles and functionalized scaffolds in medicinal chemistry and materials science.

Application

1-Bromo-3,5-dinitrobenzene serves as a valuable building block for nucleophilic aromatic substitution reactions, enabling the efficient introduction of diverse amines and thiols under mild conditions. The strong electron-withdrawing effect of the dinitro groups enhances reactivity at the bromine site, facilitating functionalization with high regioselectivity. Its bench-stable nature and compatibility with common reaction protocols make it well-suited for the synthesis of substituted heterocycles and advanced intermediates in medicinal chemistry and materials science.

Synthesis

  • Route1
    • null|null
      99-65-0
    • ~97%
    • In-stock
      1-bromo-3,5-dinitro-Benzene|CS-M0502
      18242-39-2

    References

    • MERCK SHARP and DOHME CORP.; MERCK CANADA INC.; ALTMAN, Michael, D.; ARRINGTON, Kenneth, L.; BURCH, Jason; COTE, Bernard; FOURNIER, Jean-Francois; GAUTHIER, Jacques, Yves; KATTAR, Solomon; KNOWLES, Sandra Lee; LIM, Jongwon; MACHACEK, Michelle, R.; NORTHRUP, Alan, B.; REUTERSHAN, Michael, H.; ROBICHAUD, Joel, S.; SCHELL, Adam, J.; SPENCER, Kerrie, B. Patent: WO2011/75560 A1, 2011 ; Location in patent: Page/Page column 46 ; WO 2011/075560 A1
  • Route2
    • null|null
      585-79-5
    • ~79%
    • In-stock
      1-bromo-3,5-dinitro-Benzene|CS-M0502
      18242-39-2

    References

    • de Almeida, Leonardo S.; Esteves, Pierre M.; de Mattos, Marcio C.S. Tetrahedron Letters, 2009 , vol. 50, # 25 p. 3001 - 3004
  • Route3
    • null|null
      618-87-1
    • ~91%
    • In-stock
      1-bromo-3,5-dinitro-Benzene|CS-M0502
      18242-39-2

    References

    • Baik, Woonphil; Luan, Wanqiang; Lee, Hyun Joo; Yoon, Cheol Hun; Koo, Sangho; Kim, Byeong Hyo Canadian Journal of Chemistry, 2005 , vol. 83, # 3 p. 213 - 219

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H315-H319-H332-H335
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   86.28
  • LogP   2.2655
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-bromo-3,5-dinitro-Benzene sigma1-bromo-3,5-dinitro-Benzene manufacturer1-bromo-3,5-dinitro-Benzene price1-bromo-3,5-dinitro-Benzene structure1-bromo-3,5-dinitro-Benzene SDSbuy 1-bromo-3,5-dinitro-Benzene1-bromo-3,5-dinitro-Benzene supplier1-bromo-3,5-dinitro-Benzene uses1-bromo-3,5-dinitro-Benzene molecular weightprice of 1-bromo-3,5-dinitro-Benzene1-bromo-3,5-dinitro-Benzene chemical name formula of 1-bromo-3,5-dinitro-Benzene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label