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CS-W001157 4
Total: USD 88.00

4-(Chloromethyl)pyridine hydrochloride

  • CAS No. 1822-51-1

  • Cat. No. CS-W016094
  • Purity≥95%
  • MDL No.MFCD00012826

*For research and further manufacturing use only, not for direct human use.

4-(Chloromethyl)pyridine hydrochloride|CS-W016094

Structure of 1822-51-1

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General Information

  • CAS No. 1822-51-1
  • Cat. No. CS-W016094
  • Purity ≥95%
  • MDL No. MFCD00012826
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇Cl₂N
  • Molecular Weight 164.03
  • Synonym(s) 4-Picolyl Chloride Hydrochloride
  • SMILES ClCC1=CC=NC=C1.Cl

Description

4-(Chloromethyl)pyridine hydrochloride features a pyridine ring bearing a chloromethyl group, delivering a reactive handle for nucleophilic substitution. This bench-stable salt integrates readily into synthetic sequences, enabling efficient coupling to amines and thiols under mild conditions.

Synthesis

  • Route1

    References

    • Aoki, Tsutomu; Konoike, Toshiro Patent: US2003/195363 A1, 2003 ; Location in patent: Page/Page column 13 ;
  • Route2
    • null|null
      63608-12-8
    • Pyridin-4-ylmethanol hydrochloride|CS-0699497
      62302-28-7
    • ~75%
    • In-stock
      4-(Chloromethyl)pyridine hydrochloride|CS-W016094
      1822-51-1

    References

    • Boehringer Mannheim GmbH Patent: US4243807 A1, 1981 ;
  • Route3
    • null|null
      121-44-8
    • ~%
    • In-stock
      4-(Chloromethyl)pyridine hydrochloride|CS-W016094
      1822-51-1

    References

    • US2002/183307 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.2422
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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