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5-Aminomethyl-pyridine-2-carbonitrile hydrochloride

  • CAS No. 182159-40-6

  • Cat. No. CS-0652149
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Aminomethyl-pyridine-2-carbonitrile hydrochloride|CS-0652149

Structure of 182159-40-6

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General Information

  • CAS No. 182159-40-6
  • Cat. No. CS-0652149
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈ClN₃
  • Molecular Weight 169.61
  • Synonym(s) None
  • SMILES N#CC1=NC=C(CN)C=C1.Cl

Description

5-Aminomethyl-pyridine-2-carbonitrile (hydrochloride) features a pyridine core functionalized with an aminomethyl group at the 5-position and a nitrile at the 2-position, delivering a robust scaffold for synthetic diversification. The hydrochloride salt enhances solubility and stability under standard handling conditions, enabling straightforward integration into multi-step synthesis workflows.

Application

5-Aminomethyl-pyridine-2-carbonitrile (hydrochloride) serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyridine-based scaffolds relevant in medicinal chemistry. The amine and nitrile functionalities offer orthogonal reactivity for derivatization via amidation, alkylation, or nucleophilic addition. Bench-stable and readily purified, it functions effectively in standard coupling and cyclization protocols, supporting scalable route development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   62.7
  • LogP   0.83378
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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